Engineering translational and physiologically relevant preclinical cancer models to advance women’s health research

The de la Puente Lab develops translational and physiologically relevant preclinical cancer models as tools to recapitulate tumor behavior ex vivo (“out of the living”) with an emphasis in cellular crosstalk, extracellular matrix remodeling, and spatial gradients. We focus on elucidating mechanisms driving chemoresistance and immune evasion in women’s cancer and further developing novel treatment strategies to mitigate their occurrence. Our long-term goal is to accelerate and directly translate our significant insights to aid women suffering from cancer.

Mentoring a diverse workforce of trainees that will tackle Women’s Health inequities through bioengineering approaches.

Lab News

Grant Alert!!

The lab has been awarded a 4 year American Cancer Society Research Scholar Grant. We will work on a novel biomarker panel for early detection of ovarian cancer and markers associated with chemoresistance. #Excited #ACS #OvarianCancer #SanfordResearch

Comic Book Cancer Wars

Dr. de la Puente is featured in the Comic Book Cancer Wars to bring contemporary role models for Hispanic women.
SCIENTIFIC MISSION:
Engineering translational and physiologically relevant preclinical cancer models to advance women’s health research.
LOCATION:
Sanford Research
2301 E 60th St N
Sioux Falls, SD 57104
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